NAGASAKI UNIVERSITY GLOBAL COE PROGRAM - Global Strategic Center for Radiation Health Risk Control
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Radiation Health Risk Sciences

Masahiro Nakashima, Noboru Takamura,
Kunihiro Tsukasaki, Yuji Nagayama,
Shunichi Yamashita Editors, January 2009
Hardcover: 340 pages
ISBN 978-4-431-88658-7

Contents

Overview of the Global COE Program
Global Strategic Center for Radiation Health Risk Control
    Shunichi Yamashita

Overview of the Lectures
Discussion on Points of Radiation Safety and the Scope of the University of Tokyo Global COE Program
    Toshiso Kosako and Takeshi Iimoto
Network System for Radiation Emergency Medicine in Japan and the Role of Hiroshima University
    Kenji Kamiya
Non-DNA-Targeted Effects and Low-Dose Radiation Risk
    Barry D. Michael
Update from the Chernobyl Tissue Bank: Effect of Latency on Different Types of Thyroid Cancer Post-Chernobyl
    Gerry A. Thomas
Current Risk Estimate of Radiation-Related Cancer and Our Insight into the Future
    Michiaki Kai and Nobuhiko Ban

Atomic Bomb Disease Medicine
Introduction of Atomic Bomb Disease Medical Research in Global COE Program
    Kunihiro Tsukasaki, Masahiro Nakashima, and Naoki Matsuda
The Offspring of Atomic Bomb Survivors: Cancer and Non-Cancer Mortarity and Cancer Incidence
    Akihiko Suyama, Shizue Izumi, Kojiro Koyama, Ritsu Sakata, Nobuo Nishi,
    Midori Soda, Eric J. Grant, Yukiho Shimizu, Kyoji Furukawa, Harry M. Cullings,
    Fumiyoshi Kasagi, and Kazunori Kodama
Ischemic Heart Disease Among Atomic Bomb Survivors: Possible Mechanism(s) Linking Ischemic Heart Disease and Radiation Exposure
    Masazumi Akahoshi
Leukemia, Lymphoma, and Multiple Myeloma Incidence in the LSS Cohort: 1950-2001
    Wan-Ling Hsu, Midori Soda, Nobuo Nishi, Dale Preston, Sachiyo Funamoto,
    Masao Tomonaga, Masako Iwanaga, Akihiko Suyama, and Fumiyoshi Kasagi
Follow-up Study of 78 Healthy Exposed Atomic Bomb Survivors for 35 Years in Hiroshima, With Special Reference to Multiple Cancers
    Nanao Kamada

International Radiation Health Sciences
Research Activities and Projects Within a Framework of International Radiation Health Sciences Research
    Noboru Takamura, Akira Ohtsuru, Hiroki Ozawa, and Shunichi Yamashita
Age and Prognosis: Do Adjuvant Therapies Influence the Real Prognosis?
    Robert C.F. Leonard, Mariko Morishita, and Gerry A. Thomas
Mortarlity of the Chernobyl Emergency Workers: Analysis of Dose Response by Cohort Studies Covering Follow-Up Period of 1992-2006
    Victor K. Ivanov, Sergey Yu Chekin, Valery V. Kashcheyev,
    Marat A. Maksioutov, and Anatoly F. Tsyb
Twenty Years After Chernobyl: Implications for Radiation Health Risk Control
    Yoshisada Shibata
Fallout Exporsure of the Population and Thyroid Nodular Diseases
    Zhaxybay Sh. Zhumadilov and Assem M. Orymbaeva

Radiation Basic Life Sciences, Part 1
Higher-Order Chromatin Structure and Nontargeted Effects
    Keiji Suzuki, Motohiro Yamauchi, Yasuyoshi Oka, and Shunichi Yamashita
P53 Dependency of Delayed and Untargeted Recombination in Mouse Embryos Fertilized by Irradiated Sperm
    Ohtura Niwa
The Yin and Yang of Low-Dose Radiobiology
    Tom K. Hei, Hongning Zhou, and Vladimir N. Ivanov
Induction and Persistence of Cytogenetic Damage in Mouse Splenocytes Following Whole-Body X-Irradiation Analysed by Fluorescence In Situ Hybridisation. V. Heterogeneity / Chromosome Specificity
    M. Prakash Hande and A.T. Natarajan

Cancer Research
Molecular Understanding of RET / PTC-Mediated Thyroid Carcinogenesis
    Young Suk jo, Dong Wook Kim, Min Hee Lee, Soung Jung Kim,
    Jung Hwan Hwang, and Minho Shong
Molecular Prediction of Therapeutic Response and Adverse Effect of Chemotherapy in Breast Cancer
    Yoshio Miki
Multiple Roles of NBS1 for Genotoxic and Nongenotoxic Stress
    Kenshi Komatsu, Mikio Shimada, Ken Tsuchida, Kyosuke Nakamura,
    Hiromi Yanagihara, and Junya Kobayashi

Radiation Basic Life Sciences, Part 2
The DNA Damage Response in Nontargeted Cells
    Kevin M. Prise, Giuseppe Schettino, and Susanne Burdak-Rothkamm
The Role of Telomere Dysfunction in Driving Genomic Instablity
    Susan M. Bailey, Eli S. Williams, and Robert L. Ullrich
Secretory Clusterin Is a Marker of Tumor Progression Regulated by IGF-1 and Wnt Signaling Pathways
    Yonglong Zou, Eva M. Goetz, Masatoshi Suzuki, and David A. Boothman
Target of Radiation Carcinogenesis Is Protein: Becoming Triploid Is Proximate Cause of Cell Transformation
    Masami Watanabe and Hanako Yshii
Adult Stem Cells, the Barker Hypothesis, Epigenetic Events, and Low-Level Radiation Effects
    James E. Trosko and Keiji Suzuki
Combined Effect of Ionizing Radiation and N-Ethyl-N-Nitrosourea on Mutation Induction and Lymphoma Development
    Kazumi Yamauchi, Shizuko Kakinuma, Akifumi Nakata, Tatsuhiko Imaoka,
    Takashi Takabatake, Mayumi Nishimura, and Yoshiya Shimada
Gamma-Ray-Induced Mouse Thymic Lymphomas: Bcl11b Inactivation and Prelymphoma Cells
    Ryo Kominami, Hiroyuki Ohi, Kenya Kamimura, Masaki Maruyama,
    Takashi Yamamoto, Ken-ichi Takaku, Shin-ichi Morita, Rieka Go,
    and Yukio Mishima

Radiation Risk Management
Framework of Radiation Safety Management in Japan: Laws, Administrative Agencies, and Supporting Assosiations
    Naoki Matsuda, Masahiro Yoshida, Hideaki Takao, and Miwa Miura
Background Raditaion Dose to the Population Around the Kudankulam Nuclear Power Plant
    Subramaniyan Selvasekarapandian, Jeyapandian Malathi,
    Gopalganapathi M. Brahmanandhan, and David Khanna
International Cooperation in Radiation Emergency Medical Preparedness: Establishment of a Medical Network in Asia
    Makoto Akashi

Disaster and Mental Health
Long-Term Biopsychosocial Consequences of Disaster: Focus on Atomic Bomb Survivors
    Naotaka Shinfuku
Health Status of Children Exposed to the Chernobyl Accident in Utero: Observations in 1989-2003 and the Implications for Prioritizing Prophylactic Programs
    Nataliya A. Korol and Yoshisada Shibata
Psychological Consequences More Than Half a Century After the Nagasaki Atomic Bombing
    Yuriko Suzuki, Atsuro Tsutsumi, Takashi Izutsu, and Yoshiharu Kim

Radiation and Cancer
Significance of Oncogene Amplificaitons in Breast Cancer in Atomic Bomb Survivors: Associations with Radiation Exposure and Histological Grade
    Shiro Miura, Masahiro Nakashima, Hisayoshi Kondo, Masahiro Ito,
    Serik Meirmanov, Tomayoshi Hayashi, Midori Soda, and Ichiro Sekine
Paracrine Interactions Between Normal, but Not Cancer, Epithelial and Normal Mesenchymal Cells Attenuate Radiation-Induced DNA Damage
    Vladimir A. Saenko, Yuka Nakazawa, Tatiana I. Rogounovitch, Keiji Suzuki,
    Norisato Mitsutake, Michiko Matsuse, Yasuyoshi Oka, and Shunichi Yamashita

Chernobyl and Semipalatinsk Nuclear Test Sites: Related Issues
Thyroid Cancer in Ukraine After the Chernobyl Accident: Incidence, Pathology, Treatment, and Molecular Biology
    Mykola Tronko, Tetyana Bogdanova, Ilya Likhtarev, Ihor Komisarenko,
    Andriy Kovalenko, Valentyn Markov, Valery Tereshchenko,
    Larysa Voskovoynyk, Lyudmyla Zurnadzhy, Vector Shpak,
    Lyudmyla Gulak, Rossella Elisei, Cristina Romei, and Aldo Pinchera
Current Trends in Incidence and Mortality from Thyroid Cancer in Belarus
    Pavel I. Bespalchuk, Yuri E. Demidchik, Eugene P. Demidchik,
    Vladimir A. Saenko, and Shunichi Yamashita
The Health Status of the Population in the Semey Region and Scientifically Proven Measures to Improve It
    Tolebay K. Rakhypbekov
Nuclear Explosion and Public Health Development
    Aikan Akanov, Serik Mermanov, Arslan Indershiev, Aigul Musahanova,
    and Shunichi Yamashita
 
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(in Japanese) [PDF 9MB]
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Yasuyuki Taira, Graduate Student
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